CAS 1336-21-6 · TSCA · United States of America

Ammonium hydroxide (ammonia solution) under TSCA

NH4OH (NH3 + H2O) · 氢氧化铵 / 氨水

Status: Listed. Ammonium hydroxide is on the TSCA Inventory and currently listed as TSCA Active. **OSHA PEL for ammonia at 29 CFR 1910.1000 Table Z-1: 50 ppm 8-hr TWA (verify against https://www.osha.gov/annotated-pels before relying); NIOSH REL: 25 ppm 8-hr TWA + 35 ppm STEL substantially more protective (verify against cdc.gov/niosh).** **EPA RMP threshold quantity for ammonia 20% or stronger (aqueous): 20,000 lb at 40 CFR Part 68 (verify against https://www.ecfr.gov/ before relying)**. NOT on DEA scheduling. NOT on California Proposition 65 (verify against OEHHA https://oehha.ca.gov/proposition-65/proposition-65-list before relying on negative listing). NO active US AD/CVD case on Chinese-origin ammonium hydroxide currently (verify against https://access.trade.gov/ before invoicing). Section 301 List 3 25% additional duty applies on Chinese-origin ammonium hydroxide (HS 282814) (verify against current USTR Section 301 schedule before invoicing). **EPA Clean Air Act Section 112 hazardous air pollutant (HAP) listing applies for ammonia** (verify current Section 112 HAP list against https://www.epa.gov/haps before relying). **Food-grade GRAS** under 21 CFR 184.1139 (verify against https://www.ecfr.gov/ before relying); USP / NF monograph applies for pharma-grade. Major US domestic producers: CF Industries Donaldsonville Louisiana ammonia plant + Verdigris Oklahoma + Yazoo City Mississippi, Yara North America Belle Plaine Saskatchewan import flow + Tampa Florida + Augusta Maine, Nutrien Borger Texas + Geismar Louisiana ammonia plants, Koch Fertilizer Beatrice Nebraska + Enid Oklahoma; verify each company-site pair against the producer's public website before relying.

US ammonium hydroxide lane: **OSHA PEL ammonia 50 ppm + NIOSH REL 25 ppm + 35 ppm STEL + EPA RMP 20,000 lb aqueous ≥20% + EPA Clean Air Act Section 112 HAP + Section 301 List 3 + GRAS / USP / NF**. NOT on Cal Prop 65. NO active US AD/CVD. Major US producers: CF Industries + Yara NA + Nutrien + Koch Fertilizer.

Listing and threshold

Substance Ammonium hydroxide (ammonia solution) (CAS 1336-21-6), NH4OH (NH3 + H2O)
Regime US Toxic Substances Control Act (TSCA), administered by EPA
Jurisdiction United States of America
Status Listed
Tonnage threshold CDR threshold: 25,000 lb manufactured or imported per site per year

Classifications under this regime

  • OSHA HCS: Skin Corr. 1B + Eye Dam. 1 + STOT SE 3 + Aquatic Acute 1 at ≥10% NH3
  • OSHA PEL for ammonia: 50 ppm 8-hr TWA at 29 CFR 1910.1000 Table Z-1 (verify against https://www.osha.gov/annotated-pels)
  • NIOSH REL: 25 ppm 8-hr TWA + 35 ppm STEL substantially more protective (verify against cdc.gov/niosh)
  • **EPA RMP threshold quantity for ammonia 20% or stronger (aqueous): 20,000 lb at 40 CFR Part 68** (verify against https://www.ecfr.gov/)
  • **EPA Clean Air Act Section 112 hazardous air pollutant (HAP) for ammonia** (verify current HAP list against https://www.epa.gov/haps)
  • NOT subject to TSCA Section 6 Risk Evaluation
  • NOT on DEA List I or List II
  • NOT on California Proposition 65 list (verify against OEHHA before relying on negative listing)
  • DOT 49 CFR 172.101: UN 2672 Class 8 PG III at 10-35% NH3; UN 2073 Class 2.2 at >35% NH3
  • **Food-grade GRAS** 21 CFR 184.1139 (verify against https://www.ecfr.gov/)
  • **USP / NF monograph** applies for pharma-grade
  • IARC: Not classified

Restrictions and conditions of use

  • NO active US AD/CVD case on Chinese-origin ammonium hydroxide currently
  • Section 301 List 3 25% additional duty applies on Chinese-origin ammonium hydroxide (HS 282814)
  • OSHA PEL ammonia 50 ppm + NIOSH REL 25 ppm 8-hr TWA + 35 ppm STEL
  • **EPA RMP threshold 20,000 lb for aqueous ammonia ≥20%** triggers Risk Management Plan
  • **EPA Clean Air Act Section 112 HAP for ammonia**
  • Food-grade GRAS 21 CFR 184.1139 plus USP / NF monograph for pharma-grade

Importer obligations

TSCA self-certification regime. Major US producers (verify each producer-site pair before relying): CF Industries Donaldsonville LA + Verdigris OK + Yazoo City MS, Yara North America Tampa FL + Augusta ME (plus Saskatchewan import flow), Nutrien Borger TX + Geismar LA, Koch Fertilizer Beatrice NE + Enid OK.

Required documents

  • TSCA Section 13 Import Certification on customs entry
  • OSHA SDS (Skin Corr. 1B + Eye Dam. 1 + Aquatic Acute 1)
  • CBP Form 7501 with HS 282814 + Section 301 List 3 25% duty
  • CDR filing every 4 years
  • DOT documentation for UN 2672 Class 8 PG III or UN 2073 Class 2.2
  • EPA RMP filing where applicable for aqueous ammonia ≥20% above 20,000 lb
  • FDA / USP / NF certifications for food and pharma grades

Common compliance traps

The pitfalls that have bitten importers on this lane in the past. None of these is theoretical.

  • OSHA PEL ammonia 50 ppm + NIOSH REL 25 ppm + 35 ppm STEL substantially more protective
  • **EPA RMP threshold 20,000 lb for aqueous ammonia ≥20%**
  • **EPA Clean Air Act Section 112 HAP for ammonia**
  • NO active US AD/CVD case
  • Section 301 List 3 25% additional duty applies
  • Food-grade GRAS 21 CFR 184.1139 plus USP / NF monograph for pharma-grade
  • Major US producers: CF Industries + Yara NA + Nutrien + Koch Fertilizer

Where to read next

For substance-level identifiers (formula, molecular weight, SMILES, InChIKey), GHS hazard profile, IMDG transport class, and full sourcing reference for ammonium hydroxide (ammonia solution), see the CAS 1336-21-6 sourcing reference.

For grade-by-grade buying notes, freight maths, supplier-tier pricing, and a worked landed-cost example, the ammonium hydroxide (ammonia solution) cornerstone hub covers the full sourcing chain.

For the structure and history of TSCA, see the TSCA glossary entry.

Need cross-jurisdiction compliance support on this substance? Run it through the REACH / TSCA / IECSC / AICIS / K-REACH checker, or send us the substance and the destination and we will quote FOB China and CIF / DDP landed including the regulatory work on the destination side.

Read next

Cross-jurisdiction profile and sourcing references

Referenced in

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