CAS 67-63-0 · TSCA · United States of America

Isopropyl alcohol (IPA, propan-2-ol) under TSCA

C3H8O · 异丙醇

Status: Listed. IPA is on the TSCA Inventory and currently listed as TSCA Active. **OSHA PEL 400 ppm 8-hr TWA plus 500 ppm STEL** at 29 CFR 1910.1000 Table Z-1 (verify against https://www.osha.gov/annotated-pels). NOT on EPA RMP threshold list. NOT on DEA scheduling. NOT on California Proposition 65 (verify against OEHHA https://oehha.ca.gov/proposition-65/proposition-65-list before relying on negative listing). **TRI Section 313**: IPA was DELISTED from TRI in 1993 (verify current TRI listing status against https://www.epa.gov/toxics-release-inventory-tri-program before relying). NO active US AD/CVD case on Chinese-origin IPA currently (verify against https://access.trade.gov/ before invoicing). Section 301 List 3 25% additional duty applies on Chinese-origin IPA (HS 290512). **EPA FIFRA antiseptic + sanitiser registration applies for biocidal-product applications**. FDA 21 CFR 184.1209 GRAS for food use plus FDA 21 CFR 333 OTC antiseptic monograph (Category III pending GRAS+E review; verify current status against https://www.fda.gov/drugs/over-counter-otc-nonprescription-drugs/topical-antiseptic-products before relying). Major US domestic producers (verify each company-site pair against the producer's public website before relying): ExxonMobil, Shell Chemicals, Dow Chemical, LyondellBasell, INEOS Olefins & Polymers.

The US IPA lane has **light regulatory profile**: NOT on Cal Prop 65, NOT on RMP, NOT on DEA. TRI delisted 1993. NO active US AD/CVD case. OSHA PEL 400 ppm TWA plus 500 ppm STEL. **EPA FIFRA antiseptic + sanitiser registration** for biocidal-product applications. Major US producers: ExxonMobil, Shell Chemicals, Dow Chemical, LyondellBasell, INEOS Olefins & Polymers.

Listing and threshold

Substance Isopropyl alcohol (IPA, propan-2-ol) (CAS 67-63-0), C3H8O
Regime US Toxic Substances Control Act (TSCA), administered by EPA
Jurisdiction United States of America
Status Listed
Tonnage threshold CDR threshold: 25,000 lb manufactured or imported per site per year

Classifications under this regime

  • OSHA HCS: GHS H225 / H319 / H336
  • OSHA PEL 29 CFR 1910.1000 Table Z-1: 400 ppm 8-hr TWA plus 500 ppm STEL (per https://www.osha.gov/annotated-pels)
  • NIOSH REL: 400 ppm 8-hr TWA, 500 ppm STEL (verify against https://www.cdc.gov/niosh/npg/)
  • NOT subject to TSCA Section 6 Risk Evaluation
  • NOT on EPA RMP threshold list
  • NOT on DEA List I or List II
  • NOT on California Proposition 65 list (verify against OEHHA before relying on negative listing)
  • TRI Section 313: DELISTED 1993 (verify current TRI listing status against EPA portal before relying)
  • DOT 49 CFR 172.101: UN 1219, Class 3, PG II
  • IARC: Group 3
  • FDA 21 CFR 184.1209 GRAS for food use; FDA 21 CFR 333 OTC antiseptic monograph (verify current Category status before relying)

Restrictions and conditions of use

  • OSHA-compliant SDS and workplace HazCom training required
  • NO active US AD/CVD case on Chinese-origin IPA currently
  • Section 301 List 3 25% additional duty applies on Chinese-origin IPA (HS 290512)
  • NFPA 30 Flammable and Combustible Liquids Code applies for storage
  • **EPA FIFRA antiseptic + sanitiser registration** for biocidal-product applications
  • TRI: delisted 1993; verify current status before assuming Form R reporting waiver

Importer obligations

TSCA self-certification regime. Light-regulatory profile. Major US producers: ExxonMobil, Shell Chemicals, Dow Chemical, LyondellBasell, INEOS Olefins & Polymers. **EPA FIFRA antiseptic + sanitiser registration** is the dominant downstream practitioner overhead for sanitiser product distribution.

Required documents

  • TSCA Section 13 Import Certification on customs entry
  • OSHA SDS reflecting H225 / H319 / H336
  • CBP Form 7501 with HS 290512 + Section 301 List 3 25% duty
  • CDR filing every 4 years
  • NFPA 30 storage tank documentation
  • EPA FIFRA registration documentation for biocidal-product applications
  • FDA 21 CFR 184.1209 GRAS conformity for food-grade lots; 21 CFR 333 OTC antiseptic monograph compliance

Common compliance traps

The pitfalls that have bitten importers on this lane in the past. None of these is theoretical.

  • **OSHA PEL 400 ppm TWA plus 500 ppm STEL + NFPA 30 storage**
  • TRI delisted 1993; verify current status
  • NO active US AD/CVD case on Chinese IPA currently
  • Section 301 List 3 25% additional duty applies
  • **EPA FIFRA antiseptic + sanitiser registration** for biocidal-product applications
  • Major US producers: ExxonMobil, Shell Chemicals, Dow Chemical, LyondellBasell, INEOS Olefins & Polymers

Where to read next

For substance-level identifiers (formula, molecular weight, SMILES, InChIKey), GHS hazard profile, IMDG transport class, and full sourcing reference for isopropyl alcohol (ipa, propan-2-ol), see the CAS 67-63-0 sourcing reference.

For grade-by-grade buying notes, freight maths, supplier-tier pricing, and a worked landed-cost example, the isopropyl alcohol (ipa, propan-2-ol) cornerstone hub covers the full sourcing chain.

For the structure and history of TSCA, see the TSCA glossary entry.

Need cross-jurisdiction compliance support on this substance? Run it through the REACH / TSCA / IECSC / AICIS / K-REACH checker, or send us the substance and the destination and we will quote FOB China and CIF / DDP landed including the regulatory work on the destination side.

Read next

Cross-jurisdiction profile and sourcing references

Referenced in

6 pages across the Sourzi moat

This term shows up in 4 regulatory pages, 1 topic clusters, 1 CAS profiles. Sample backlinks per content type below.

Regulatory (4)

Plus 1 more regulatory pages.

Topic cluster (1)

CAS (1)

Free download

Free PDF: the same MSDS verification template the Sourzi team uses to cross-reference factory documents against TSCA, REACH, AICIS, and CDR before booking.