CAS 7553-56-2 · K-REACH · Republic of Korea

Iodine (I2) under K-REACH

I2 · 碘

Status: Registered. Iodine is registered under K-REACH. **Drug Precursor scheduling under Korean Act on Control of Narcotics (마약류 관리에 관한 법률) administered by MFDS + Ministry of Justice; verify exact category + concentration threshold against https://www.mfds.go.kr/ before invoicing.** NO active Korean AD/CVD case on Chinese-origin iodine; Korea is structurally a net-importer with significant import dependency on Chile (SQM) + Japan (Iwate / Chiba gas-well) + China (limited supply) for pharma + LCD-polariser-PVA-film + animal-feed + disinfectant sectors. KCFTA preferential zero-duty applies for Chinese-origin imports.

K-REACH treats iodine as a registered substance with **Drug Precursor permit overlay under Korean Act on Control of Narcotics (verify exact category + concentration threshold against MFDS)**. Korea is structurally a net-importer; primary sources Chile (SQM Atacama caliche-ore) + Japan (Iwate / Chiba gas-well) + China (limited). **Iodine distinguishing pattern across all 5 regimes**: Globally extracted from Chilean caliche-ore brines (SQM Atacama dominant) + Japanese gas-well brines (Iwate + Chiba) + US Oklahoma gas-well brines (Iofina) + Russian gas-well brines; China is structurally a net-importer; **Drug Precursor / essential-chemical scheduling overlay across US (DEA List II, 21 CFR 1310.02(b), 0.4 kg cumulative reporting threshold) + China (易制毒化学品管理条例 2005, MPS + NMPA + SAMR) + Australia (Crimes (Drug Precursors) Act 2008, Department of Home Affairs EUD) + Korea (Act on Control of Narcotics, MFDS)** while EU is NOT scheduled (Reg 273/2004 + Reg 2015/1011 do NOT cover iodine); **pharma (iohexol + iopromide + amiodarone contrast media + povidone-iodine) + LCD-polariser-PVA-film (Korea LG Display / Samsung Display major buyer) + animal-feed (EDDI + iodised salt via KIO3 / KI) + disinfectant downstream chains** with mid hazard profile (Skin Irrit. 2 + Eye Irrit. 2 + STOT SE 3 + Acute Tox. 4 inhalation) + IARC not classified + ADR / DOT / GB / ADG / KCS UN 3495 Class 8 PG III + USP / Ph. Eur. / ChP / KP / JP pharma-grade overlay.

Listing and threshold

Substance Iodine (I2) (CAS 7553-56-2), I2
Regime Korea Act on the Registration and Evaluation of Chemicals (Act No. 11789, "K-REACH" amended 2018)
Jurisdiction Republic of Korea
Status Registered
Tonnage threshold K-REACH registration required for existing chemicals manufactured or imported >1 tonne/year (verified per Korean Ministry of Environment / NIER guidance, https://chemical.chemlinked.com/chempedia/k-reach; threshold for new substances was reduced from 0.1 t/y to 1 t/y effective 1 January 2025 per K-REACH 2025 amendment)

Classifications under this regime

  • Korean GHS classification: Skin Irrit. 2 + Eye Irrit. 2 + STOT SE 3 + Acute Tox. 4 inhalation (verify against current MoE / NIER GHS before relying)
  • **Drug Precursor scheduling under Korean Act on Control of Narcotics (마약류 관리에 관한 법률); verify exact category + concentration threshold against https://www.mfds.go.kr/ before relying**
  • NOT typically on Korea TCCA Toxic Chemicals list at elemental level (verify against the current TCCA Toxic Chemicals list at https://www.nics.go.kr/ before relying)
  • Korean Customs Service (KCS) HS code: 280120
  • Korean MoEL OEL: 0.1 ppm ceiling typically (verify against current MoEL Industrial Safety + Health Act OEL list at https://www.moel.go.kr/ before relying)
  • **KP (Korean Pharmacopoeia) monograph** for pharma-grade iodine + iodine tincture + povidone-iodine
  • IARC: Not classified

Restrictions and conditions of use

  • **Drug Precursor permit + record-keeping required under Korean Act on Control of Narcotics** (verify exact category + concentration threshold against https://www.mfds.go.kr/ before invoicing)
  • KOSHA MSDS in Korean required at workplace (Skin Irrit. 2 + Eye Irrit. 2 + STOT SE 3 + Acute Tox. 4 inhalation)
  • NO active Korean AD/CVD case on Chinese-origin iodine; Korea is structurally a net-importer
  • KCFTA preferential zero-duty applies (HS 280120)
  • Korean DOT-equivalent UN 3495 Class 8 PG III where consigned in transport quantity

Importer obligations

Korean importer of record must hold K-REACH registration + **Drug Precursor permit under Korean Act on Control of Narcotics**. Korea is structurally a net-importer with significant Chile (SQM) + Japan (Iwate / Chiba gas-well) + China (limited) import dependency.

Required documents

  • K-REACH registration number on Korean side
  • **Drug Precursor permit (MFDS + Ministry of Justice)** per Korean Act on Control of Narcotics
  • Korean MSDS (Skin Irrit. 2 + Eye Irrit. 2 + STOT SE 3 + Acute Tox. 4 inhalation)
  • KCS declaration with HS 280120
  • China-Korea FTA Form CO
  • KP monograph documentation where pharma-grade

Common compliance traps

The pitfalls that have bitten importers on this lane in the past. None of these is theoretical.

  • **Drug Precursor permit + record-keeping required under Korean Act on Control of Narcotics (verify exact category + concentration threshold against https://www.mfds.go.kr/)**
  • Korea is structurally a net-importer with significant Chile (SQM) + Japan + China import dependency
  • KCFTA preferential zero-duty applies
  • NO active Korean AD/CVD case
  • NOT typically on TCCA Toxic Chemicals list at elemental level
  • **Pharma + LCD-polariser-film (Korea is a major LCD-polariser producer; LG Display + Samsung Display) + animal-feed + povidone-iodine disinfectant downstream chains**

Where to read next

For substance-level identifiers (formula, molecular weight, SMILES, InChIKey), GHS hazard profile, IMDG transport class, and full sourcing reference for iodine (i2), see the CAS 7553-56-2 sourcing reference.

For grade-by-grade buying notes, freight maths, supplier-tier pricing, and a worked landed-cost example, the iodine (i2) cornerstone hub covers the full sourcing chain.

For the structure and history of K-REACH, see the K-REACH glossary entry.

Need cross-jurisdiction compliance support on this substance? Run it through the REACH / TSCA / IECSC / AICIS / K-REACH checker, or send us the substance and the destination and we will quote FOB China and CIF / DDP landed including the regulatory work on the destination side.

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Free PDF: the same MSDS verification template the Sourzi team uses to cross-reference factory documents against TSCA, REACH, AICIS, and CDR before booking.