CAS 1071-83-6 · REACH · European Union

Glyphosate under REACH

C3H8NO5P · 草甘膦

Status: Registered. Glyphosate is fully registered under REACH. **Distinguishing pattern: N-(phosphonomethyl)glycine is the world's most-used systemic broad-spectrum herbicide active ingredient (commercial brand Roundup); used as glyphosate-acid + isopropylamine salt + potassium salt + ammonium salt formulations; primary mode of action is inhibition of EPSP synthase (5-enolpyruvylshikimate-3-phosphate synthase) in the shikimate pathway, which exists in plants + fungi + some bacteria but NOT in mammals. Glyphosate-tolerant genetically-modified crops (Roundup Ready soybean, corn, cotton, canola) drove explosive growth of glyphosate use post-1996.** **EU active-substance authorisation under Plant Protection Products Regulation (EC) No 1107/2009 was renewed for 10 years via Commission Implementing Regulation (EU) 2023/2660 of 28 November 2023, effective 16 December 2023, expiring 15 December 2033** (sourced to EUR-Lex https://eur-lex.europa.eu/eli/reg_impl/2023/2660 to verify; replaced earlier 5-year renewal Reg (EU) 2017/2324). **IARC: Group 2A (probably carcinogenic to humans), Monograph Volume 112 (2015)** (sourced to https://monographs.iarc.who.int/wp-content/uploads/2018/06/mono112-10.pdf to verify). **The IARC 2A classification + EFSA + ECHA + EU Member State assessments find glyphosate NOT classified as carcinogen or mutagen at EU CLP level reflects the substantive scientific divergence that has driven the multi-jurisdiction political controversy** (verify exact current EU CLP harmonised classification against ECHA Annex VI to CLP Table 3.1 before relying). NOT SVHC. NOT Annex XIV. NO active EU AD case on Chinese-origin glyphosate currently (verify against EUR-Lex before invoicing).

Glyphosate is fully REACH-registered. **EU Plant Protection Products Regulation active substance authorisation renewed for 10 years via Commission Implementing Reg (EU) 2023/2660, effective 16 December 2023, expiring 15 December 2033** (sourced to EUR-Lex). **IARC Group 2A Monograph Volume 112 (2015) (sourced); divergent from EU CLP non-classification as carcinogen / mutagen; substantive scientific divergence drives multi-jurisdiction political controversy**. NOT SVHC, NOT Annex XIV. **Member state product authorisations separate; some member states maintain stricter retail / public-space use-restrictions**. **China dominant global glyphosate producer (~60%)**: Zhejiang Wynca + Hubei Sanonda + Sichuan Hebang + Anhui Zealous + Jiangsu Good Harvest-Weien + Sichuan Leshan Fuhua + Hubei Tianyaorui.

Listing and threshold

Substance Glyphosate (CAS 1071-83-6), C3H8NO5P
Regime EU Regulation (EC) No 1907/2006: Registration, Evaluation, Authorisation and Restriction of Chemicals
Jurisdiction European Union (EU-27 plus EEA: Iceland, Liechtenstein, Norway)
Status Registered
Tonnage threshold Registration required for any importer or manufacturer placing >1 t/year on the EU market

Classifications under this regime

  • Eye Dam. 1: H318 + Aquatic Chronic 2: H411 per harmonised CLP at EU level (verify exact harmonised classification against ECHA Annex VI to CLP Table 3.1 before relying; the EU CLP NON-classification as carcinogen / mutagen is the substantive divergence from the IARC 2A finding)
  • **IARC: Group 2A (probably carcinogenic to humans), Monograph Volume 112 (2015)** (sourced to https://monographs.iarc.who.int/wp-content/uploads/2018/06/mono112-10.pdf to verify)
  • **EU Plant Protection Products Regulation (EC) No 1107/2009: glyphosate active substance authorisation renewed for 10 years via Commission Implementing Regulation (EU) 2023/2660 of 28 November 2023, effective 16 December 2023, expiring 15 December 2033** (sourced to EUR-Lex https://eur-lex.europa.eu/eli/reg_impl/2023/2660 to verify)
  • ADR / RID: NOT regulated as dangerous goods at solid form; aquatic toxicity may apply for solutions (verify against current ADR at https://unece.org/transport/dangerous-goods/adr-2025-files before consigning)

Restrictions and conditions of use

  • NOT on REACH Annex XIV authorisation list (verify against ECHA https://echa.europa.eu/authorisation-list)
  • NOT classified as SVHC (verify against ECHA https://echa.europa.eu/candidate-list-table)
  • NOT subject to any Annex XVII restriction
  • NO active EU AD case on Chinese-origin glyphosate currently (verify against EUR-Lex https://eur-lex.europa.eu/ before invoicing)
  • **EU Plant Protection Products Regulation: glyphosate active substance authorisation valid 16 December 2023 to 15 December 2033 per Reg (EU) 2023/2660; member state product authorisations are separate (some member states maintain stricter use-restrictions on glyphosate at retail / public-space level)**
  • NOT in CBAM Phase 1 scope

Importer obligations

A non-EU producer cannot register directly under REACH. The EU importer of record must hold a registration or rely on an Only Representative (OR). **EU Plant Protection Products Regulation product authorisation per member state required for placing on market as plant protection product** (verify against member-state competent authority before invoicing). Major non-Chinese producers: Bayer Crop Science (USA Soda Springs ID + Camacari Brazil + Antwerp Belgium), Syngenta (Switzerland Munchwilen + India + China), Nufarm (Australia + Brazil), Adama (Israel + China). Major Chinese glyphosate producers (China is the dominant global producer with ~60% global capacity): Zhejiang Wynca (Hangzhou Zhejiang) + Hubei Sanonda (Hubei Jingzhou) + Sichuan Hebang (Sichuan) + Anhui Zealous + Jiangsu Good Harvest-Weien (Yangzhou) + Sichuan Leshan Fuhua + Hubei Tianyaorui; verify each producer-site pair against the producer's public website before relying.

Required documents

  • REACH registration number on EU side
  • SDS (Eye Dam. 1 + Aquatic Chronic 2 + IARC 2A reference)
  • Customs entry HS code 293299 (glyphosate as N-phosphonomethyl-glycine; verify exact HS subheading against current EU TARIC; some Member States use 293499)
  • **EU Plant Protection Product authorisation per member state where placed on market as PPP**
  • Cosmetic / food-contact restrictions where applicable per member-state legislation

Common compliance traps

The pitfalls that have bitten importers on this lane in the past. None of these is theoretical.

  • **IARC Group 2A (probably carcinogenic) Monograph Volume 112 (2015) divergent from EU CLP non-classification as carcinogen / mutagen**
  • **EU active-substance authorisation Reg (EU) 2023/2660 effective 16 December 2023 expiring 15 December 2033 (10-year renewal); member state product authorisations separate**
  • NOT SVHC, NOT Annex XIV, NO active EU AD
  • Eye Dam. 1 + Aquatic Chronic 2 only at EU CLP harmonised level
  • **N-(phosphonomethyl)glycine systemic broad-spectrum herbicide; EPSP synthase inhibitor in shikimate pathway; glyphosate-tolerant GM crops (Roundup Ready soybean + corn + cotton + canola) drove post-1996 use explosion downstream chain**
  • Major Chinese producers (~60% global): Zhejiang Wynca Hangzhou + Hubei Sanonda Jingzhou + Sichuan Hebang + Anhui Zealous + Jiangsu Good Harvest-Weien Yangzhou + Sichuan Leshan Fuhua + Hubei Tianyaorui

Where to read next

For substance-level identifiers (formula, molecular weight, SMILES, InChIKey), GHS hazard profile, IMDG transport class, and full sourcing reference for glyphosate, see the CAS 1071-83-6 sourcing reference.

For grade-by-grade buying notes, freight maths, supplier-tier pricing, and a worked landed-cost example, the glyphosate cornerstone hub covers the full sourcing chain.

For the structure and history of REACH, see the REACH glossary entry.

Need cross-jurisdiction compliance support on this substance? Run it through the REACH / TSCA / IECSC / AICIS / K-REACH checker, or send us the substance and the destination and we will quote FOB China and CIF / DDP landed including the regulatory work on the destination side.

Referenced in

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