CAS 1071-83-6 · TSCA · United States of America

Glyphosate under TSCA

C3H8NO5P · 草甘膦

Status: Active. Glyphosate is on the TSCA Active Inventory. **California Proposition 65 listing: glyphosate added 7 July 2017 as carcinogen** (sourced to OEHHA Proposition 65 List https://oehha.ca.gov/proposition-65/proposition-65-list to verify; the OEHHA listing relied on the IARC 2A 2015 finding). **California Cal Prop 65 warning litigation: National Association of Wheat Growers v. Becerra (2020 + ongoing)** held the Cal Prop 65 carcinogen warning compelled-speech requirement unconstitutional as applied to glyphosate (NOR-PROOF case-history; verify current status of warning enforcement against current OEHHA + Cal Department of Justice guidance). **IARC Group 2A Monograph Volume 112 (2015)** (sourced to https://monographs.iarc.who.int/wp-content/uploads/2018/06/mono112-10.pdf to verify). **EPA conclusion: glyphosate not likely to be carcinogenic to humans (Interim Registration Review Decision 2020); however EPA RED was vacated by Ninth Circuit Natural Resources Defense Council v. EPA (June 2022) and remanded for further review** (verify current EPA registration-review status against https://www.epa.gov/pesticide-reevaluation before relying). **US litigation: Bayer-Monsanto Roundup litigation, multiple settlement programs totaling $10.9 billion 2020 to 2021 plus continuing trial-court verdicts** (verify exact current settlement totals against verified financial reporting before relying). **EPA FIFRA registered as herbicide active**; major US producers Bayer Crop Science (Soda Springs ID + Muscatine IA glyphosate sourced from Soda Springs).

Glyphosate is TSCA-Active with **California Proposition 65 listing 7 July 2017 as carcinogen (sourced to OEHHA, subject to ongoing First Amendment compelled-speech litigation NAWG v. Becerra) + IARC Group 2A Monograph Volume 112 (2015) (sourced) + EPA RED vacated by Ninth Circuit June 2022 NRDC v. EPA remanded for further review + Bayer-Monsanto Roundup litigation $10.9 billion 2020 to 2021 settlement programs plus continuing trial-court verdicts (verify exact current settlement totals before relying)**. NO active US AD/CVD on Chinese-origin glyphosate. **Cal Prop 65 + EPA registration-review remand + ongoing US Roundup litigation are the practical US-channel compliance pivots. Multi-jurisdiction political controversy reflects substantive scientific divergence on cancer-classification.**

Listing and threshold

Substance Glyphosate (CAS 1071-83-6), C3H8NO5P
Regime US Toxic Substances Control Act (TSCA), administered by EPA
Jurisdiction United States of America
Status Active
Tonnage threshold TSCA Section 8(a) Chemical Data Reporting (CDR) at >25,000 lb/year per US site

Classifications under this regime

  • TSCA Active Inventory
  • **California Proposition 65 listing: glyphosate added 7 July 2017 as carcinogen** (sourced to OEHHA https://oehha.ca.gov/proposition-65/proposition-65-list)
  • **IARC Group 2A Monograph Volume 112 (2015)** (sourced to https://monographs.iarc.who.int/wp-content/uploads/2018/06/mono112-10.pdf)
  • **EPA conclusion: glyphosate not likely to be carcinogenic to humans (Interim Registration Review Decision 2020); EPA RED vacated by Ninth Circuit June 2022 and remanded** (verify current registration-review status against https://www.epa.gov/pesticide-reevaluation before relying)
  • OSHA PEL: not specifically established for glyphosate (verify against https://www.osha.gov/annotated-pels before relying)
  • NIOSH REL: not specifically established (verify against current https://www.cdc.gov/niosh/npg/)
  • ACGIH TLV-TWA: 5 mg/m3 inhalable + 5 mg/m3 respirable typically (verify against current ACGIH TLV documentation at https://www.acgih.org/ before relying)
  • **EPA FIFRA registered as herbicide active; multiple Section 24c special-local-need + Section 18 emergency-exemption registrations active across states** (verify against https://www.epa.gov/pesticide-registration before relying)
  • DOT 49 CFR: NOT regulated as dangerous goods at solid form

Restrictions and conditions of use

  • **California Proposition 65 carcinogen warning required where placed in California consumer + workplace channel above safe-harbor NSRL** (subject to ongoing First Amendment compelled-speech litigation; verify current enforcement status against OEHHA + Cal DOJ before invoicing)
  • NO active US AD/CVD case on Chinese-origin glyphosate currently (verify against access.trade.gov before invoicing)
  • **EPA FIFRA registration required where placed as herbicide; current registration-review status under remand from Ninth Circuit June 2022** (verify against https://www.epa.gov/pesticide-reevaluation)
  • EPA RCRA: glyphosate is NOT RCRA-listed waste (verify against ecfr.gov 40 CFR 261 before relying)
  • EPA TRI reporting threshold (verify against https://www.epa.gov/toxics-release-inventory-tri-program)
  • Section 232 not applicable

Importer obligations

TSCA Section 13 import certification (positive). **EPA FIFRA registration mandatory where placed as herbicide active; importer must hold current FIFRA registration or be the registered importer of record on EPA registration certificate.** **California Proposition 65 carcinogen warning labelling for Chinese-origin glyphosate placed in California channel above safe-harbor NSRL** (subject to ongoing compelled-speech litigation). Major non-Chinese producers: Bayer Crop Science (USA Soda Springs ID + Camacari Brazil + Antwerp Belgium), Syngenta (USA + Switzerland Munchwilen + India + China), Nufarm (Australia + Brazil), Adama (Israel + China). Major Chinese exporters: Zhejiang Wynca + Hubei Sanonda + Sichuan Hebang + Anhui Zealous + Jiangsu Good Harvest-Weien + Sichuan Leshan Fuhua + Hubei Tianyaorui.

Required documents

  • TSCA Section 13 import certification
  • CBP entry HS 293299 (glyphosate as organic phosphonate)
  • SDS (Eye Dam. 1 + Aquatic Chronic 2 + IARC 2A reference + Cal Prop 65 carcinogen 7 July 2017)
  • **California Proposition 65 carcinogen warning label where placed in California channel above safe-harbor NSRL**
  • **EPA FIFRA registration certificate** (verify against https://www.epa.gov/pesticide-registration)
  • EPA TRI reporting documentation where placed at threshold

Common compliance traps

The pitfalls that have bitten importers on this lane in the past. None of these is theoretical.

  • **California Proposition 65 listing 7 July 2017 as carcinogen sourced to OEHHA; Cal Prop 65 warning subject to ongoing First Amendment compelled-speech litigation (NAWG v. Becerra)**
  • **IARC Group 2A Monograph Volume 112 (2015) sourced**
  • **EPA RED vacated by Ninth Circuit June 2022 NRDC v. EPA, remanded for further review; current EPA registration-review status fluid**
  • **Bayer-Monsanto Roundup litigation, $10.9 billion 2020 to 2021 settlement programs plus continuing trial-court verdicts** (verify exact current settlement totals before relying)
  • NO active US AD/CVD case on Chinese-origin glyphosate currently
  • EPA FIFRA registered as herbicide active
  • NOT RCRA-listed waste; NOT regulated as dangerous goods at solid form
  • **Glyphosate-tolerant GM crops (Roundup Ready soybean + corn + cotton + canola) drove post-1996 use explosion in US Midwest agriculture downstream chain**

Where to read next

For substance-level identifiers (formula, molecular weight, SMILES, InChIKey), GHS hazard profile, IMDG transport class, and full sourcing reference for glyphosate, see the CAS 1071-83-6 sourcing reference.

For grade-by-grade buying notes, freight maths, supplier-tier pricing, and a worked landed-cost example, the glyphosate cornerstone hub covers the full sourcing chain.

For the structure and history of TSCA, see the TSCA glossary entry.

Need cross-jurisdiction compliance support on this substance? Run it through the REACH / TSCA / IECSC / AICIS / K-REACH checker, or send us the substance and the destination and we will quote FOB China and CIF / DDP landed including the regulatory work on the destination side.

Referenced in

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