CAS 7681-49-4 · K-REACH · Republic of Korea

Sodium fluoride (NaF) under K-REACH

NaF · 氟化钠

Status: Registered. Sodium fluoride is registered under K-REACH. **Korea TCCA Toxic Chemicals list status: verify against the current TCCA Toxic Chemicals list at https://www.nics.go.kr/ and NICS toxic-chemical database before relying** (NaF's Acute Tox. 3 + STOT RE 2 hazard profile may trigger TCCA scheduling). NOT on Korean Drug Management Act precursor list. NO active Korean AD/CVD case on Chinese-origin sodium fluoride currently. Korea has limited domestic sodium fluoride production; structurally net-importer with significant Chinese-origin import dependency. KCFTA preferential zero-duty applies for Chinese-origin imports. **Korean MFDS regulates sodium fluoride as an OTC anti-caries active** (verify against MFDS before relying).

K-REACH treats sodium fluoride as a registered substance with **TCCA Toxic Chemicals scheduling potentially applicable** (verify against NICS database). Korea net-importer with significant Chinese-origin dependency. NO active Korean AD/CVD case. **NaF distinguishing pattern across all 5 regimes**: Production via HF batch 85 + NaOH batch 1 / Na2CO3 batch 36 → NaF + H2O + alongside fluorine chain feedstock for fluoride-chemistry downstream + toothpaste / dental caries-prevention agent ~30% + municipal water-fluoridation + glass / enamel flux + pesticide / wood-preservative + pharma + rust-inhibitor + electroplating-additive downstream chains + moderate hazard profile across regimes (Acute Tox. 3 oral + STOT RE 2 skeletal fluorosis chronic high exposure + Skin Irrit. 2 + Eye Irrit. 2; UN 1690 Class 6.1 PG III) + IARC not classified + US OSHA PEL 2.5 mg/m3 + NIOSH REL 2.5 mg/m3 + FDA OTC anti-caries 21 CFR 355 + EPA FIFRA wood-preservative + EU Cosmetic Products Regulation Annex III F-cap toothpaste 0.15% adult / 0.10% child + Australian SUSMP Schedule 6 industrial / unscheduled toothpaste + TGA anti-caries + Korean MFDS anti-caries.

Listing and threshold

Substance Sodium fluoride (NaF) (CAS 7681-49-4), NaF
Regime Korea Act on the Registration and Evaluation of Chemicals (Act No. 11789, "K-REACH" amended 2018)
Jurisdiction Republic of Korea
Status Registered
Tonnage threshold K-REACH registration required for existing chemicals manufactured or imported >1 tonne/year (verified per Korean Ministry of Environment / NIER guidance, https://chemical.chemlinked.com/chempedia/k-reach; threshold for new substances was reduced from 0.1 t/y to 1 t/y effective 1 January 2025 per K-REACH 2025 amendment)

Classifications under this regime

  • Korean GHS classification: Acute Tox. 3 oral + STOT RE 2 + Skin Irrit. 2 + Eye Irrit. 2
  • **Korea TCCA Toxic Chemicals list status: verify against NICS toxic-chemical database before relying**
  • NOT on Korean Drug Management Act precursor list
  • Korean Customs Service (KCS) HS code: 282619
  • **Korean MFDS OTC anti-caries active** (verify against MFDS before relying)
  • IARC: Not classified

Restrictions and conditions of use

  • TCCA Toxic Chemicals Handling Permit obligations may apply where TCCA-scheduled (verify TCCA status against NICS database)
  • KOSHA MSDS in Korean required at workplace (Acute Tox. 3 oral + STOT RE 2)
  • NO active Korean AD/CVD case on Chinese sodium fluoride currently
  • KCFTA preferential zero-duty applies (HS 282619)
  • **Korean MFDS OTC anti-caries active**

Importer obligations

Korean importer of record must hold K-REACH registration. Korea has limited domestic sodium fluoride production; structurally net-importer with significant Chinese-origin import dependency.

Required documents

  • K-REACH registration number on Korean side
  • Korean MSDS (Acute Tox. 3 oral + STOT RE 2)
  • KCS declaration with HS 282619
  • China-Korea FTA Form CO
  • MFDS OTC anti-caries active certification where applicable

Common compliance traps

The pitfalls that have bitten importers on this lane in the past. None of these is theoretical.

  • Korea has limited domestic sodium fluoride production; structurally net-importer with Chinese-origin dependency
  • KCFTA preferential zero-duty applies
  • NO active Korean AD/CVD case
  • **Korea TCCA Toxic Chemicals list status: verify against NICS database**
  • **Korean MFDS OTC anti-caries active**

Where to read next

For substance-level identifiers (formula, molecular weight, SMILES, InChIKey), GHS hazard profile, IMDG transport class, and full sourcing reference for sodium fluoride (naf), see the CAS 7681-49-4 sourcing reference.

For grade-by-grade buying notes, freight maths, supplier-tier pricing, and a worked landed-cost example, the sodium fluoride (naf) cornerstone hub covers the full sourcing chain.

For the structure and history of K-REACH, see the K-REACH glossary entry.

Need cross-jurisdiction compliance support on this substance? Run it through the REACH / TSCA / IECSC / AICIS / K-REACH checker, or send us the substance and the destination and we will quote FOB China and CIF / DDP landed including the regulatory work on the destination side.

Read next

Cross-jurisdiction profile and sourcing references

Referenced in

5 pages across the Sourzi moat

This term shows up in 4 regulatory pages, 1 CAS profiles. Sample backlinks per content type below.

Regulatory (4)

Plus 1 more regulatory pages.

CAS (1)

Free download

Free PDF: the same MSDS verification template the Sourzi team uses to cross-reference factory documents against TSCA, REACH, AICIS, and CDR before booking.