Sodium fluoride (NaF) under TSCA
NaF · 氟化钠
Status: Listed. Sodium fluoride is on the TSCA Inventory and currently listed as TSCA Active. **OSHA PEL for fluoride compounds at 29 CFR 1910.1000 Table Z-1: 2.5 mg/m3 8-hr TWA expressed as F (verify against https://www.osha.gov/annotated-pels before relying); NIOSH REL: 2.5 mg/m3 8-hr TWA (verify against cdc.gov/niosh).** NOT on EPA RMP threshold list. NOT on DEA scheduling. **Sodium fluoride IS on the California Proposition 65 list for developmental toxicity** (listing date in the early 1990s; verify exact listing date and endpoint against OEHHA https://oehha.ca.gov/proposition-65/proposition-65-list before relying). NO active US AD/CVD case on Chinese-origin sodium fluoride currently (verify against https://access.trade.gov/ before invoicing). Section 301 List 3 25% additional duty applies on Chinese-origin sodium fluoride (HS 282619) (verify against current USTR Section 301 schedule before invoicing). **FDA recognises sodium fluoride as an OTC anti-caries active under 21 CFR 355 Anticaries Drug Products Final Monograph** (verify against https://www.ecfr.gov/ before relying); USP / NF monograph applies for pharma-grade. **EPA FIFRA registers sodium fluoride as a wood-preservative pesticide active** (verify current FIFRA registration status against https://www.epa.gov/pesticide-registration before relying). Major US domestic producers: Solvay Specialty Phosphates US operations, ICL Performance Products US operations (verify each company-site pair against the producer's public website before relying).
US sodium fluoride lane: **OSHA PEL 2.5 mg/m3 + NIOSH REL 2.5 mg/m3 + FDA OTC anti-caries active 21 CFR 355 + EPA FIFRA wood-preservative pesticide active + Section 301 List 3 + UN 1690 Class 6.1 PG III**. **On Cal Prop 65 for developmental toxicity** (verify exact date against OEHHA before relying). NO active US AD/CVD. Major US producers: Solvay Specialty Phosphates + ICL Performance Products.
Listing and threshold
| Substance | Sodium fluoride (NaF) (CAS 7681-49-4), NaF |
|---|---|
| Regime | US Toxic Substances Control Act (TSCA), administered by EPA |
| Jurisdiction | United States of America |
| Status | Listed |
| Tonnage threshold | CDR threshold: 25,000 lb manufactured or imported per site per year |
Classifications under this regime
- OSHA HCS: Acute Tox. 3 oral + STOT RE 2 + Skin Irrit. 2 + Eye Irrit. 2
- OSHA PEL for fluoride compounds: 2.5 mg/m3 8-hr TWA as F at 29 CFR 1910.1000 Table Z-1 (verify against https://www.osha.gov/annotated-pels)
- NIOSH REL: 2.5 mg/m3 8-hr TWA (verify against cdc.gov/niosh)
- NOT subject to TSCA Section 6 Risk Evaluation
- NOT on EPA RMP threshold list
- NOT on DEA List I or List II
- On California Proposition 65 for developmental toxicity (verify exact listing date against OEHHA https://oehha.ca.gov/proposition-65/proposition-65-list before relying)
- DOT 49 CFR 172.101: UN 1690 Class 6.1 PG III
- **FDA OTC anti-caries active 21 CFR 355 Anticaries Drug Products Final Monograph** (verify against https://www.ecfr.gov/)
- **USP / NF monograph** applies for pharma-grade
- **EPA FIFRA wood-preservative pesticide active** (verify current FIFRA registration status against https://www.epa.gov/pesticide-registration)
- IARC: Not classified
Restrictions and conditions of use
- NO active US AD/CVD case on Chinese-origin sodium fluoride currently
- Section 301 List 3 25% additional duty applies on Chinese-origin sodium fluoride (HS 282619)
- OSHA PEL 2.5 mg/m3 8-hr TWA as F + NIOSH REL 2.5 mg/m3
- **FDA OTC anti-caries active 21 CFR 355**
- **EPA FIFRA wood-preservative pesticide active**
Importer obligations
TSCA self-certification regime. Major US producers: Solvay Specialty Phosphates US operations, ICL Performance Products US operations.
Required documents
- TSCA Section 13 Import Certification on customs entry
- OSHA SDS (Acute Tox. 3 oral + STOT RE 2 + Skin Irrit. 2 + Eye Irrit. 2)
- CBP Form 7501 with HS 282619 + Section 301 List 3 25% duty
- CDR filing every 4 years
- DOT documentation for UN 1690 Class 6.1 PG III
- FDA 21 CFR 355 + USP / NF certifications for OTC anti-caries / pharma grades
- EPA FIFRA registration where placed as wood-preservative pesticide active
Common compliance traps
The pitfalls that have bitten importers on this lane in the past. None of these is theoretical.
- OSHA PEL 2.5 mg/m3 + NIOSH REL 2.5 mg/m3 8-hr TWA as F
- NO active US AD/CVD case
- Section 301 List 3 25% additional duty applies
- **FDA OTC anti-caries active 21 CFR 355 Anticaries Drug Products Final Monograph**
- **EPA FIFRA wood-preservative pesticide active**
- Major US producers: Solvay Specialty Phosphates + ICL Performance Products
Where to read next
For substance-level identifiers (formula, molecular weight, SMILES, InChIKey), GHS hazard profile, IMDG transport class, and full sourcing reference for sodium fluoride (naf), see the CAS 7681-49-4 sourcing reference.
For grade-by-grade buying notes, freight maths, supplier-tier pricing, and a worked landed-cost example, the sodium fluoride (naf) cornerstone hub covers the full sourcing chain.
For the structure and history of TSCA, see the TSCA glossary entry.
Need cross-jurisdiction compliance support on this substance? Run it through the REACH / TSCA / IECSC / AICIS / K-REACH checker, or send us the substance and the destination and we will quote FOB China and CIF / DDP landed including the regulatory work on the destination side.
Read next
Cross-jurisdiction profile and sourcing references
Regulatory
Sodium fluoride (NaF) under REACH
European Union listing status, classifications, importer obligations.
Regulatory
Sodium fluoride (NaF) under IECSC
People's Republic of China listing status, classifications, importer obligations.
Regulatory
Sodium fluoride (NaF) under AICIS
Australia listing status, classifications, importer obligations.
Regulatory
Sodium fluoride (NaF) under K-REACH
Republic of Korea listing status, classifications, importer obligations.
CAS
CAS 7681-49-4 sourcing reference
Identifiers, hazard profile, IMDG transport class, and supplier geography for Sodium fluoride (NaF).
Glossary
TSCA, Toxic Substances Control Act
US federal law that gives the EPA authority to track and restrict the manufacture, import, processing, distribution, and disposal of industrial chemicals.
Referenced in
5 pages across the Sourzi moat
This term shows up in 4 regulatory pages, 1 CAS profiles. Sample backlinks per content type below.
Regulatory (4)
Sodium fluoride (NaF) under REACH
European Union compliance profile for Sodium fluoride (NaF).
Sodium fluoride (NaF) under IECSC
People's Republic of China compliance profile for Sodium fluoride (NaF).
Sodium fluoride (NaF) under AICIS
Australia compliance profile for Sodium fluoride (NaF).
Plus 1 more regulatory pages.
Free download
Free PDF: the same MSDS verification template the Sourzi team uses to cross-reference factory documents against TSCA, REACH, AICIS, and CDR before booking.